Nicotinamide Riboside (NR) is a nucleoside made out of
niacinamide and ribose. It is a form of Vitamin B3 and is
a precursor to nicotinamide adenine dinucleotide which
means it is needed to make NAD+, increased NAD+ then
activates the following enzymes.
• Sirtuins, a potential anti-aging target
• PARPs, which may repair damaged DNA
• CD38, a receptor in the immune system which is involved
in glucose-induced insulin secretion
Because Sirt1 activates PGC-1alpha, scientists are
investigating if NR supplementation stimulates
mitochondrial biogenesis and improves mitochondrial
health. Scientists have explored its effects on generating
energy in mitochondrial-dense tissues like muscle, brain,
and liver.
Benefits
· Stimulates NAD+ Metabolism
· Improves Exercise Performance
· Boosts Cognitive Health